David Sinclair
30 tracked predictions · 0 hit · 0 partial · 0 miss · 30 still open
open David Sinclair: Continuous predictive health monitoring via wearables and related technology will become normal practice, allowing people to receive treatment (e.g., before a heart attack) before an event occurs.
“I think eventually it'll be normal to be monitored and you know to have something that tells you ahead of time if you might have a heart attack next week you could go in and get a medicine before it actually happens. That's the future.”
Your call:
open David Sinclair: ER100 gene therapy will be tested as a treatment to reverse GLP-1-associated blindness.
“That's one of the conditions that ER100 therapy will be tested to see if we can reverse blindness.”
Your call:
open David Sinclair: His former student's (Wang Tan Lu's) paper on macular degeneration reversal will be published soon.
“My former student who left and went to MIT, Wang Tang Lu, has a paper that he's hopefully going to publish soon.”
Your call:
open David Sinclair: Life Biosciences plans to try ER100 therapy in additional eye diseases, including glaucoma, pending current results.
“That's also on the radar of Life Biosciences to try ER100 in those diseases, you know, pending results in glaucoma.”
Your call:
open David Sinclair: Ongoing lab work rejuvenating sensory nerves is expected to reveal broad, measurable body-wide effects that provide a scientific mechanism for benefits long attributed to meditation.
“We expect to see broad effects on the body that... meditation has been saying for potentially thousands of years, uh, is a good thing.”
Your call:
open David Sinclair: Science will eventually produce evidence, if not proof, that the mind can overcome the body and cure diseases that medicines alone cannot.
“I believe that there will be evidence, if not proof, that how the mind overcomes matter and can do remarkable things like cure diseases that even medicines cannot.”
Your call:
open David Sinclair: Age-reversal pills based on this reprogramming technology will become available within our lifetime.
“I can see a future where, certainly within our lifetime, we'll have these pills available.”
Your call:
open David Sinclair: 2026 may be the year humanity learns that age reversal is possible in humans.
“It may be sooner than we think. It may be 2026 is the year we learn that age reversal is possible in humans.”
Your call:
open David Sinclair: Doctors may know within about 6 weeks of dosing whether the ER100 eye gene therapy works in humans.
“You only need 6 weeks. So, in 6 weeks, some doctor may even know the answer whether this works in humans.”
Your call:
open David Sinclair: His small-molecule age-reversal cocktail will enter a human clinical trial within a couple of months, as part of the Healthspan Xprize.
“Those we hope to put into a clinical trial into humans within the next couple of months as part of our Xprize competition.”
Your call:
open David Sinclair: The eventual longevity small-molecule drug will become as cheap and widely accessible as metformin, potentially costing only cents per pill.
“I don't want to say how much, but one day I hope that it'll be like metformin, which is pretty cheap. Anyone on the planet could afford it.”
Your call:
open David Sinclair: The eventual longevity pill could be priced around a couple hundred dollars a month.
“You predicted a couple hundred bucks a month as a potential range.”
Your call:
open David Sinclair: Humans may eventually be able to live for hundreds, possibly thousands, of years.
“It feels weird to say we can live hundreds of years, maybe thousands of years.”
Your call:
open David Sinclair: As more safety data accumulates, reprogramming therapy will eventually be deliverable intravenously as a whole-body treatment rather than tissue by tissue.
“I don't see a reason why, as we learn more and we see more safety, that we couldn't go, you know, intravenously.”
Your call:
open David Sinclair: People will live into the 22nd century, thanks to advancements in longevity science.
“Teenager today will live into the 22nd century.”
Your call:
open David Sinclair: Within the next 10 years, we'll have the ability to use gene therapy throughout the body.
“And we're already working at Life Biosciences on getting away from viral delivery, which is the current one.”
Your call:
open David Sinclair: In 10 years, you just take a pill for 4 weeks and you get younger.
“In fact, I can see how this is going to happen. That's what we're working towards in my lab.”
Your call:
open David Sinclair: We will see more funding coming in for age reversal research both philanthropically and investment-wise.
“I'm hopeful that we'll see a lot more funding coming in, uh, from from people both philanthropically and investment wise.”
Your call:
open David Sinclair: A pill for rejuvenation from blood factors will be developed.
“We're trying to turn that into a pill, but stay tuned for that.”
Your call:
open David Sinclair: Unity Biosciences will continue to develop their technology and find something promising.
“I think they'll keep pushing on and they'll find something.”
Your call:
open David Sinclair: Life Biosciences will submit an IND and start human trials by the end of the year.
“We're planning to submit what's called an IND shortly. And uh hopefully by this time next year, we'll know if it's working because the studies are straight into patients.”
Your call:
open David Sinclair: The company will make mice live 10 times longer, but the challenge is to apply this to mammals.
“Ultimately we want to make mice live times longer, 10 times longer, live.”
Your call:
open David Sinclair: The US could solve its debt by giving people an extra 20 years of health.
“The US could solve the US debt by giving people an extra 20 years of health.”
Your call:
open David Sinclair: The next decade will see significant advancements in longevity research due to rapid technological progress.
“The next 10 healthy years to intercept those technologies.”
Your call:
open David Sinclair: They will reach longevity escape velocity within 5 years.
“It's about 5 years ago. It it was published 3 years ago.”
Your call:
open David Sinclair: A clinical trial for age reversal in humans to cure blindness will be tested in 18 months to two years.
“we'll be um in the next 18 months or two years testing our first age reversal uh clinical trial in humans um to cure blindness.”
Your call:
open David Sinclair: A whole-body rejuvenation therapy will be developed.
“I think a whole body reset is coming.”
Your call:
open David Sinclair: Achieving cheap, safe, and effective age slowing and age reversal within the next 5 to 10 years.
“over the next 5 to 10 years to be able to achieve uh cheap safe effective age slowing and age reversal”
Your call:
open David Sinclair: Age reversal treatments will exist and be accessible to some segment of the public in 10 years.
“10 years beautiful so that's what that's what Ray said, George had it at about 15”
Your call:
open David Sinclair: Continuous monitoring of thousands of analyses will be common in the future.
“we're going to be monitoring thousands of analyes constantly and it's all going to your AI that is optimizing your life if you wanted to if you don't you want to be a couch potato that is your option but you should have the option to actually maximize your health buddy”
Your call: